Sabine Plöttner, PhD

Research Scientist

Centre of Toxicology

Education

• "Fachtoxikologin DGPT" and European Registered Toxicologist, 2010
• Ph.D., Heinrich-Heine-University Düsseldorf, Germany, 2006
  Doctoral thesis in the Department of Toxicology, Institute for Occupational Physiology at the University of Dortmund (IfADo), 2002-2006
• Collegiate in the International Graduate School "Molecular Mechanisms of Food Toxicology", Heinrich-Heine-University Düsseldorf, 2002-2005
• MSc., Biology, Ruhr-University Bochum, 2000

E-mail

Research

The focus of my scientific work is in the field of cell biology with particular emphasis on the question whether hazardous substances influence the cell cycle and apoptosis. Genotoxic and mutagenic substances may interact with DNA and lead to aberrant cell growth. This may in turn result in cancer development. An arrest in cell cycle progression enables the cell to repair damaged DNA and thereby avoids propagation of mutations. Another mechanism to avoid manifestation of deleterious mutations is by induction of apoptosis. Methods for the measurement of alterations in cell cycle progression and induction of apoptosis will be established. The overall goal is to determine whether chemical substances at the workplace are able to influence the cell cycle and to induce apoptosis, respectively, and to gain insight into their modes of action.

Memberships

• Society of Toxicology (SOT)
• European Environmental Mutagenesis and Genomics Society (EEMGS)
• Federation of European Toxicologists & European Societies of Toxicology (EUROTOX)
• Deutsche Gesellschaft für Arbeitsmedizin und Umweltmedizin e.V. (DGAUM)
• Gesellschaft für Toxikologie (GT) in der Deutschen Gesellschaft für klinische und experimentelle Pharmakologie und Toxikologie e. V. (DGPT)
• Gesellschaft für Umwelt-Mutationsforschung e. V. (GUM)
• Verband Biologie, Biowissenschaften & Biomedizin in Deutschland (VBIO)

Selected Publications

View my collection, "My Bibliography" from NCBI

Languages

German, English, French